Activation of the Notch signaling pathway in the anterior cingulate cortex is involved in the pathological process of neuropathic pain

Activation of the Notch signaling pathway in the anterior cingulate cortex is involved in the pathological process of neuropathic pain

Plastic changes in the anterior cingulate cortex (ACC) is very important in hypersensitivity to pain caused by peripheral nerve injury. The Notch signaling pathway has been shown to regulate differentiation and synaptic transmission. Therefore, this study was to investigate the function of Notch signaling pathway in the ACC during nociceptive transmission caused by neuropathy pain

.We adopt Western boltting, N- [N- (3,5-difluorophenacetyl) l-Alanyl] -S- Phenylglycine t-butyl ester (dAPT) microinjections, RNA interference targeting Notch1, hairy and enhancer of split (Hes) 1 or Hes5, electrophysiological recording and behavioral tests to verify the relationship between Notch signaling in the ACC and neuropathic pain in rats adult male Sprague Dawley .Levels of Notch intracellular domain (NICD) increased in the ACC at day 7 after chronic constriction injury (CCI) operation or spared nerve injury (SNI).

Meanwhile, the mRNA level of Notch signaling downstream effector Hes1 Hes5 mRNA increased while the rate unchanged. Injection of DAPT, a γ-Secretase (the key enzyme involved in the Notch pathway) inhibitors, ACC to significantly reversed neuropathic pain behavior. Intra-ACC injection of short hairpin RNA (shRNA) -Notch reduce the expression of NICD and lower potentiation of synaptic transmission in the ACC. In addition, the perception of pain is also addressed in mice undergoing CCI or SNI. This process is mainly mediated by Hes1 downstream effectors, but not Hes5.Based this result, activation of the Notch / Hes1 signaling pathway in the ACC participated in the development of neuropathic pain, suggesting that Notch pathway may be a new therapeutic target to treat chronic pain.

Activation of the Notch signaling pathway in the anterior cingulate cortex is involved in the pathological process of neuropathic pain
Activation of the Notch signaling pathway in the anterior cingulate cortex is involved in the pathological process of neuropathic pain

[Decrease in long chains MALAT1 non-coding RNA expression and increased expression of HSA-miR155-3p involved in the regulation of Notch signaling pathway in patients with rheumatoid arthritis]

Objective To investigate the expression of a long chain of non-coding RNA (lncRNA) metastasis associated lung adenocarcinoma transcript 1 (MALAT1) and HSA-miR155-3p in patients with rheumatoid arthritis (RA) and their relationship with the Notch signaling pathway, and explore the possibility of RA pathogenesis. Method peripheral blood of patients with RA (RA group) and healthy controls (group NC) was used to screen differentially expressed mRNA by lncRNA and high-throughput gene sequencing.

Reverse-transcription PCR is used to detect the expression of lncRNA MALAT1, HSA-miR155-3p and Notch signaling pathway receptor ligands. Results lncRNA sequencing analysis showed a total of 9158 lncRNAs are expressed differently. Gene ontology (GO) annotation of functional classification revealed that differential mRNA is expressed mainly involved in inflammatory immune response, cellular transcriptional regulation and so on.

path analysis proves that the differentially expressed mRNA was significantly associated with genes involved in rheumatoid arthritis, cellular aging, and the Notch signaling pathway. According to the prediction of cis and trans, Jagged1-2, Delta1-2 and Notch1-2 probably closely related to RA. MALAT1 the RA group was lower than in group NC, and HSA-miR155-3p expression was significantly higher than in the NC group.

Transfection Collection™ : Notch1/CSL Transient Pack (Notch Signaling Pathway)

79285 500 rxns.
EUR 715
Description: The Notch1/CSL Transient Packis designed to provide the tools necessary for transiently transfecting and monitoring the activity of the Notch signaling pathway in HEK293 cultured cells. The kit contains transfection-ready vectors containing firefly luciferase as a Notch pathway-responsive reporter and constitutively expressing Renilla luciferase as a transfection control. It also includes the Dual Luciferase detection reagents to detect both luciferase activities and specialized medium for growing and assaying HEK293 cells._x000D_The key to the Notch1/CSL Transient Pack is the expression vector for NOTCH1 that has a deletion of the entire extracellular domain (Notch1DE). Inside the cells, the NOTCH1 DE can be cleaved by γ-secretase and active NOTCH1 NICD is released into the nucleus. The kit also contains CSL (CBF1/RBP-Jk) luciferase reporter vector, which is a Notch pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized CSL responsive elements upstream of a minimal promoter. The CSL (CBF1/RBP-Jk) reporter is premixed with constitutively expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency._x000D_The pack also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical for determining pathway specific effects and background luciferase activity._x000D_Additionally, the pack includes cell culture medium (BPS Medium 1) that has been optimized for use with HEK293 cells*. BPS Medium 1 includes MEM medium, 10% fetal bovine serum, 1% non-essential amino acids, sodium pyruvate, and 1% Pen/Strep. Finally, the pack provides the Dual Luciferase (Firefly-Renilla) Assay System. These luciferase reagents provide highly sensitive, stable detection of firefly luciferase activity and Renilla luciferase activity. The dual luciferase reagents can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required. _x000D_*Note: the kit may be used with other cell lines than HEK293, but an alternate cell culture medium may be required for optimal cell growth,

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1406.4

LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles

RA900A-1 20 profiles
EUR 1020

Mouse LncRNA Profiler qPCR Array Kit (cDNA synthesis kit and qPCR array) 20 profiles

RA930A-1 20 profiles
EUR 1020

LncRNA Profiler Complete qPCR Array Kit (cDNA synthesis kit, qPCR array and SYBR Green reagent) 20 profiles

RA910A-1 20 profiles
EUR 1329.6

Pig Agouti signaling protein(ASIP) ELISA kit

E07A1721-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Agouti signaling protein(ASIP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Agouti signaling protein(ASIP) ELISA kit

E07A1721-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Agouti signaling protein(ASIP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Agouti signaling protein(ASIP) ELISA kit

E07A1721-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Agouti signaling protein(ASIP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Suppressors Of Cytokine Signaling 1

E01A42683 96T
EUR 700
Description: ELISA

Guinea Pig Suppressors Of Cytokine Signaling 1

E05S0138-48wellsplate 48 wells plate
EUR 280

Guinea Pig Suppressors Of Cytokine Signaling 1

E05S0138-96wellsplate 96 wells plate
EUR 405

Pig Suppressor of cytokine signaling 2 ELISA Kit

MBS2882378-10x96StripWells 10x96-Strip-Wells
EUR 4630

Pig Suppressor of cytokine signaling 2 ELISA Kit

MBS2882378-48StripWells 48-Strip-Wells
EUR 440

Pig Suppressor of cytokine signaling 2 ELISA Kit

MBS2882378-5x96StripWells 5x96-Strip-Wells
EUR 2480

Pig Suppressor of cytokine signaling 2 ELISA Kit

MBS2882378-96StripWells 96-Strip-Wells
EUR 580

Guinea Pig Agouti signaling protein(ASIP) ELISA kit

E01A36067 96T
EUR 700
Description: ELISA

Guinea pig Agouti signaling protein(ASIP) ELISA kit

E05A1721-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Agouti signaling protein(ASIP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Agouti signaling protein(ASIP) ELISA kit

E05A1721-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Agouti signaling protein(ASIP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Agouti signaling protein(ASIP) ELISA kit

E05A1721-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Agouti signaling protein(ASIP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Suppressors Of Cytokine Signaling 3 ELISA kit

E07S0137-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Suppressors Of Cytokine Signaling 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Suppressors Of Cytokine Signaling 3 ELISA kit

E07S0137-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Suppressors Of Cytokine Signaling 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Suppressors Of Cytokine Signaling 3 ELISA kit

E07S0137-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Suppressors Of Cytokine Signaling 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Suppressors Of Cytokine Signaling 1 ELISA kit

E07S0138-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Suppressors Of Cytokine Signaling 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Suppressors Of Cytokine Signaling 1 ELISA kit

E07S0138-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Suppressors Of Cytokine Signaling 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Suppressors Of Cytokine Signaling 1 ELISA kit

E07S0138-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Suppressors Of Cytokine Signaling 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Agouti signaling protein(ASIP) ELISA kit

E05A1721-48wellsplate 48 wells plate
EUR 280

Guinea Pig Agouti signaling protein(ASIP) ELISA kit

E05A1721-96wellsplate 96 wells plate
EUR 405

Pig Regulator Of G Protein Signaling 4 ELISA kit

E07R0039-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Regulator Of G Protein Signaling 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator Of G Protein Signaling 4 ELISA kit

E07R0039-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Regulator Of G Protein Signaling 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator Of G Protein Signaling 4 ELISA kit

E07R0039-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Regulator Of G Protein Signaling 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA Kit for Pig Suppressor of cytokine signaling 2

E1415p 96T
EUR 441.6

Recombinant Pig Suppressor of cytokine signaling 2 (SOCS2)

MBS1472887-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1120

Recombinant Pig Suppressor of cytokine signaling 2 (SOCS2)

MBS1472887-002mgEColi 0.02mg(E-Coli)
EUR 700

Recombinant Pig Suppressor of cytokine signaling 2 (SOCS2)

MBS1472887-002mgYeast 0.02mg(Yeast)
EUR 870

Recombinant Pig Suppressor of cytokine signaling 2 (SOCS2)

MBS1472887-01mgEColi 0.1mg(E-Coli)
EUR 835

Recombinant Pig Suppressor of cytokine signaling 2 (SOCS2)

MBS1472887-01mgYeast 0.1mg(Yeast)
EUR 1020

Pig Suppressor of cytokine signaling 2 (SOCS2) ELISA Kit

abx516783-96tests 96 tests
EUR 687.5

Pig Suppressor of cytokine signaling 2, SOCS2 ELISA Kit

MBS9339673-10x96StripWells 10x96-Strip-Wells
EUR 6725

Pig Suppressor of cytokine signaling 2, SOCS2 ELISA Kit

MBS9339673-48StripWells 48-Strip-Wells
EUR 550

Pig Suppressor of cytokine signaling 2, SOCS2 ELISA Kit

MBS9339673-5x96StripWells 5x96-Strip-Wells
EUR 3420

Pig Suppressor of cytokine signaling 2, SOCS2 ELISA Kit

MBS9339673-96StripWells 96-Strip-Wells
EUR 765

Pig Regulator of G Protein Signaling 4 (RGS4) ELISA Kit

abx360740-96tests 96 tests
EUR 990

ELISA Kit for Pig Regulator of G-protein signaling 2

E15385p 96T
EUR 441.6

Guinea Pig Suppressors Of Cytokine Signaling 3 ELISA kit

E01A42682 96T
EUR 700
Description: ELISA

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA kit

E05S0137-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Suppressors Of Cytokine Signaling 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA kit

E05S0137-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Suppressors Of Cytokine Signaling 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA kit

E05S0137-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Suppressors Of Cytokine Signaling 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Suppressors Of Cytokine Signaling 1 ELISA kit

E05S0138-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Suppressors Of Cytokine Signaling 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Suppressors Of Cytokine Signaling 1 ELISA kit

E05S0138-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Suppressors Of Cytokine Signaling 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Suppressors Of Cytokine Signaling 1 ELISA kit

E05S0138-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Suppressors Of Cytokine Signaling 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E07W0001-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine WNT1 Inducible Signaling Pathway Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E07W0001-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine WNT1 Inducible Signaling Pathway Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E07W0001-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine WNT1 Inducible Signaling Pathway Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Suppressors Of Cytokine Signaling 1 ELISA Kit

MBS7258113-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea Pig Suppressors Of Cytokine Signaling 1 ELISA Kit

MBS7258113-48StripWells 48-Strip-Wells
EUR 485

Guinea Pig Suppressors Of Cytokine Signaling 1 ELISA Kit

MBS7258113-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea Pig Suppressors Of Cytokine Signaling 1 ELISA Kit

MBS7258113-96StripWells 96-Strip-Wells
EUR 690

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA Kit

MBS732880-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA Kit

MBS732880-48StripWells 48-Strip-Wells
EUR 485

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA Kit

MBS732880-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea pig Suppressors Of Cytokine Signaling 3 ELISA Kit

MBS732880-96StripWells 96-Strip-Wells
EUR 690

Guinea Pig Suppressors Of Cytokine Signaling 3 ELISA kit

E05S0137-48wellsplate 48 wells plate
EUR 280

Guinea Pig Suppressors Of Cytokine Signaling 3 ELISA kit

E05S0137-96wellsplate 96 wells plate
EUR 405

Pig Regulator of G protein signaling 17(RGS17) ELISA kit

E07R0408-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Regulator of G protein signaling 17(RGS17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator of G protein signaling 17(RGS17) ELISA kit

E07R0408-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Regulator of G protein signaling 17(RGS17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator of G protein signaling 17(RGS17) ELISA kit

E07R0408-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Regulator of G protein signaling 17(RGS17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator of G protein signaling 20(RGS20) ELISA kit

E07R0409-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Regulator of G protein signaling 20(RGS20) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator of G protein signaling 20(RGS20) ELISA kit

E07R0409-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Regulator of G protein signaling 20(RGS20) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Regulator of G protein signaling 20(RGS20) ELISA kit

E07R0409-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Regulator of G protein signaling 20(RGS20) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig RGS2/Regulator of G-protein signaling 2 ELISA Kit

MBS2904458-10x96StripWells 10x96-Strip-Wells
EUR 4630

Pig RGS2/Regulator of G-protein signaling 2 ELISA Kit

MBS2904458-48StripWells 48-Strip-Wells
EUR 440

Pig RGS2/Regulator of G-protein signaling 2 ELISA Kit

MBS2904458-5x96StripWells 5x96-Strip-Wells
EUR 2480

Pig RGS2/Regulator of G-protein signaling 2 ELISA Kit

MBS2904458-96StripWells 96-Strip-Wells
EUR 580

Pig Regulator of G-protein signaling 5, RGS5 ELISA Kit

MBS9336078-10x96StripWells 10x96-Strip-Wells
EUR 6725

Pig Regulator of G-protein signaling 5, RGS5 ELISA Kit

MBS9336078-48StripWells 48-Strip-Wells
EUR 550

Pig Regulator of G-protein signaling 5, RGS5 ELISA Kit

MBS9336078-5x96StripWells 5x96-Strip-Wells
EUR 3420

Pig Regulator of G-protein signaling 5, RGS5 ELISA Kit

MBS9336078-96StripWells 96-Strip-Wells
EUR 765

Pig Regulator of G-protein signaling 2, RGS2 ELISA Kit

MBS9328245-10x96StripWells 10x96-Strip-Wells
EUR 6725

Pig Regulator of G-protein signaling 2, RGS2 ELISA Kit

MBS9328245-48StripWells 48-Strip-Wells
EUR 550

Pig Regulator of G-protein signaling 2, RGS2 ELISA Kit

MBS9328245-5x96StripWells 5x96-Strip-Wells
EUR 3420

Pig Regulator of G-protein signaling 2, RGS2 ELISA Kit

MBS9328245-96StripWells 96-Strip-Wells
EUR 765

Recombinant Pig Regulator of G-protein signaling 2 (RGS2)

MBS1389380-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1130

Recombinant Pig Regulator of G-protein signaling 2 (RGS2)

MBS1389380-002mgEColi 0.02mg(E-Coli)
EUR 715

Recombinant Pig Regulator of G-protein signaling 2 (RGS2)

MBS1389380-002mgYeast 0.02mg(Yeast)
EUR 885

Recombinant Pig Regulator of G-protein signaling 2 (RGS2)

MBS1389380-01mgEColi 0.1mg(E-Coli)
EUR 860

Recombinant Pig Regulator of G-protein signaling 2 (RGS2)

MBS1389380-01mgYeast 0.1mg(Yeast)
EUR 1035

Recombinant Pig Regulator of G-protein signaling 5 (RGS5)

MBS1333343-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1100

Recombinant Pig Regulator of G-protein signaling 5 (RGS5)

MBS1333343-002mgEColi 0.02mg(E-Coli)
EUR 700

Recombinant Pig Regulator of G-protein signaling 5 (RGS5)

MBS1333343-002mgYeast 0.02mg(Yeast)
EUR 855

Recombinant Pig Regulator of G-protein signaling 5 (RGS5)

MBS1333343-01mgEColi 0.1mg(E-Coli)
EUR 810

Recombinant Pig Regulator of G-protein signaling 5 (RGS5)

MBS1333343-01mgYeast 0.1mg(Yeast)
EUR 1000

Guinea Pig Regulator Of G Protein Signaling 4 ELISA kit

E01A42385 96T
EUR 700
Description: ELISA

Guinea Pig Regulator Of G Protein Signaling 1 ELISA kit

E01A42600 96T
EUR 700
Description: ELISA

Guinea pig Regulator Of G Protein Signaling 4 ELISA kit

E05R0039-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator Of G Protein Signaling 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator Of G Protein Signaling 4 ELISA kit

E05R0039-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator Of G Protein Signaling 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator Of G Protein Signaling 4 ELISA kit

E05R0039-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator Of G Protein Signaling 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator Of G Protein Signaling 4 ELISA Kit

MBS730614-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea pig Regulator Of G Protein Signaling 4 ELISA Kit

MBS730614-48StripWells 48-Strip-Wells
EUR 485

Guinea pig Regulator Of G Protein Signaling 4 ELISA Kit

MBS730614-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea pig Regulator Of G Protein Signaling 4 ELISA Kit

MBS730614-96StripWells 96-Strip-Wells
EUR 690

Guinea Pig Regulator Of G Protein Signaling 4 ELISA kit

E05R0039-48wellsplate 48 wells plate
EUR 280

Guinea Pig Regulator Of G Protein Signaling 4 ELISA kit

E05R0039-96wellsplate 96 wells plate
EUR 405

Guinea Pig Regulator Of G Protein Signaling 1 ELISA kit

E05R0626-48wellsplate 48 wells plate
EUR 280

Guinea Pig Regulator Of G Protein Signaling 1 ELISA kit

E05R0626-96wellsplate 96 wells plate
EUR 405

Guinea pig suppressor of cytokine signaling 6 (SOCS6) ELISA Kit

MBS2613011-10x96StripWells 10x96-Strip-Wells
EUR 3545

Guinea pig suppressor of cytokine signaling 6 (SOCS6) ELISA Kit

MBS2613011-48StripWells 48-Strip-Wells
EUR 310

Guinea pig suppressor of cytokine signaling 6 (SOCS6) ELISA Kit

MBS2613011-5x96StripWells 5x96-Strip-Wells
EUR 1940

Guinea pig suppressor of cytokine signaling 6 (SOCS6) ELISA Kit

MBS2613011-96StripWells 96-Strip-Wells
EUR 475

Guinea pig Suppressors of Cytokine Signaling 3 (SOCS3) ELISA Kit

abx357380-96tests 96 tests
EUR 990

Guinea pig SOCS3 (Suppressors of Cytokine Signaling 3) ELISA Kit

MBS2509244-10x96Tests 10x96Tests
EUR 4445

Guinea pig SOCS3 (Suppressors of Cytokine Signaling 3) ELISA Kit

MBS2509244-24Tests 24Tests
EUR 280

Guinea pig SOCS3 (Suppressors of Cytokine Signaling 3) ELISA Kit

MBS2509244-48Tests 48Tests
EUR 495

Guinea pig SOCS3 (Suppressors of Cytokine Signaling 3) ELISA Kit

MBS2509244-5x96Tests 5x96Tests
EUR 2480

Guinea pig SOCS3 (Suppressors of Cytokine Signaling 3) ELISA Kit

MBS2509244-96Tests 96Tests
EUR 585

Guinea pig Regulator of G Protein Signaling 4 (RGS4) ELISA Kit

abx357487-96tests 96 tests
EUR 990

Guinea pig RGS4 (Regulator of G Protein Signaling 4) ELISA Kit

MBS2502621-10x96Tests 10x96Tests
EUR 4445

Guinea pig RGS4 (Regulator of G Protein Signaling 4) ELISA Kit

MBS2502621-24Tests 24Tests
EUR 280

Guinea pig RGS4 (Regulator of G Protein Signaling 4) ELISA Kit

MBS2502621-48Tests 48Tests
EUR 495

Guinea pig RGS4 (Regulator of G Protein Signaling 4) ELISA Kit

MBS2502621-5x96Tests 5x96Tests
EUR 2480

Guinea pig RGS4 (Regulator of G Protein Signaling 4) ELISA Kit

MBS2502621-96Tests 96Tests
EUR 585

Guinea Pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E01A43598 96T
EUR 700
Description: ELISA

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E05W0001-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig WNT1 Inducible Signaling Pathway Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E05W0001-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig WNT1 Inducible Signaling Pathway Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E05W0001-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig WNT1 Inducible Signaling Pathway Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA Kit

MBS753483-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA Kit

MBS753483-48StripWells 48-Strip-Wells
EUR 485

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA Kit

MBS753483-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea pig WNT1 Inducible Signaling Pathway Protein 1 ELISA Kit

MBS753483-96StripWells 96-Strip-Wells
EUR 690

Guinea Pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E05W0001-48wellsplate 48 wells plate
EUR 280

Guinea Pig WNT1 Inducible Signaling Pathway Protein 1 ELISA kit

E05W0001-96wellsplate 96 wells plate
EUR 405

Guinea Pig Regulator of G protein signaling 17(RGS17) ELISA kit

E01A42507 96T
EUR 700
Description: ELISA

Guinea Pig Regulator of G protein signaling 20(RGS20) ELISA kit

E01A42508 96T
EUR 700
Description: ELISA

Guinea pig Regulator of G protein signaling 17(RGS17) ELISA kit

E05R0408-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator of G protein signaling 17(RGS17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator of G protein signaling 17(RGS17) ELISA kit

E05R0408-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator of G protein signaling 17(RGS17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator of G protein signaling 17(RGS17) ELISA kit

E05R0408-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator of G protein signaling 17(RGS17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator of G protein signaling 20(RGS20) ELISA kit

E05R0409-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator of G protein signaling 20(RGS20) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator of G protein signaling 20(RGS20) ELISA kit

E05R0409-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator of G protein signaling 20(RGS20) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator of G protein signaling 20(RGS20) ELISA kit

E05R0409-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Regulator of G protein signaling 20(RGS20) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Regulator of G-protein signaling 5 (RGS5) ELISA Kit

MBS2607093-10x96StripWells 10x96-Strip-Wells
EUR 3545

Guinea pig Regulator of G-protein signaling 5 (RGS5) ELISA Kit

MBS2607093-48StripWells 48-Strip-Wells
EUR 310

Guinea pig Regulator of G-protein signaling 5 (RGS5) ELISA Kit

MBS2607093-5x96StripWells 5x96-Strip-Wells
EUR 1940

Guinea pig Regulator of G-protein signaling 5 (RGS5) ELISA Kit

MBS2607093-96StripWells 96-Strip-Wells
EUR 475

Guinea Pig Regulator of G protein signaling 17(RGS17) ELISA kit

E05R0408-48wellsplate 48 wells plate
EUR 280

Guinea Pig Regulator of G protein signaling 17(RGS17) ELISA kit

E05R0408-96wellsplate 96 wells plate
EUR 405

Guinea Pig Regulator of G protein signaling 20(RGS20) ELISA kit

E05R0409-48wellsplate 48 wells plate
EUR 280

Guinea Pig Regulator of G protein signaling 20(RGS20) ELISA kit

E05R0409-96wellsplate 96 wells plate
EUR 405

Guinea pig Regulator of G-protein signaling 20 (RGS20) ELISA Kit

MBS7218733-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea pig Regulator of G-protein signaling 20 (RGS20) ELISA Kit

MBS7218733-48StripWells 48-Strip-Wells
EUR 485

Guinea pig Regulator of G-protein signaling 20 (RGS20) ELISA Kit

MBS7218733-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea pig Regulator of G-protein signaling 20 (RGS20) ELISA Kit

MBS7218733-96StripWells 96-Strip-Wells
EUR 690

Guinea pig Regulator of G-protein signaling 17 (RGS17) ELISA Kit

MBS7230579-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea pig Regulator of G-protein signaling 17 (RGS17) ELISA Kit

MBS7230579-48StripWells 48-Strip-Wells
EUR 485

Delta1 Notch ligand expression lines, Delta2 Jagged1, Jagged2 and receptor Notch1 and Notch2 in the RA group increases. Correlation analysis showed that HSA-miR155-3p is inversely proportional to MALAT1, HSA-miR155-3p is directly proportional to the Notch pathway Delta1, Jagged1, and MALAT1 is inversely proportional to Jagged2. Conclusions In patients with rheumatoid arthritis, lncRNA MALAT1 HSA-mir155-3p reduced and increased, which together regulate Notch signaling pathway changes.

Anthony

Related Posts

fallback-image

IMMUNOGLOBULINS

Increased Expression of Fibulin-1 Is Associated With Hepatocellular Carcinoma Progression by Regulating the Notch Signaling Pathway

Increased Expression of Fibulin-1 Is Associated With Hepatocellular Carcinoma Progression by Regulating the Notch Signaling Pathway

Andrographolide Inhibits Proliferation of Colon Cancer SW-480 Cells via Downregulating Notch Signaling Pathway

Andrographolide Inhibits Proliferation of Colon Cancer SW-480 Cells via Downregulating Notch Signaling Pathway

TWIST1 correlates with Notch signaling pathway to develop esophageal squamous cell carcinoma

TWIST1 correlates with Notch signaling pathway to develop esophageal squamous cell carcinoma

No Comment

Leave a Reply

Your email address will not be published.

Tags

December 2024
M T W T F S S
 1
2345678
9101112131415
16171819202122
23242526272829
3031  

Recent Posts

Categories

Pages