Notch signaling pathway

elegans lin-12, informed by the first oncogenic mutation affecting a human Notch gene

SPON2 Is Upregulated through Notch Signaling Pathway and Promotes Tumor Progression in Gastric Cancer

SPON2 Is Upregulated through Notch Signaling Pathway and Promotes Tumor Progression in Gastric Cancer

Spondin-2 (SPON2) involved in cancer development and metastasis of many tumors; However, the role and the underlying mechanisms in gastric cancer is still unclear. In this study, we examined the role SPON2 and associated signaling pathway in gastric cancer progression and metastasis. SPON2 expression level was found to be regulated in gastric cancer cell lines and tissues of patients compared to gastric epithelial cells of normal and normal controls.

Furthermore, SPON2 silencing was observed to reduce cell proliferation and motility and reduce tumor growth in xenograft mice. Conversely, excess SPON2 found to increase cell proliferation and motility. Next, we focus on regulatory mechanisms SPON2 in gastric cancer. cDNA microarray and in vitro studies suggest that Notch signaling was significantly correlated with the expression SPON2.

Therefore, we confirm how Notch signaling pathway regulates the expression of Notch-related SPON2 using signaling interactions of transcription factors and reporter gene assay. In addition, activation of Notch signaling is observed to increase cell proliferation, migration, and invasion through SPON2 expression. Our study suggests that Notch signaling-mediated upregulation SPON2 associated with aggressive development of gastric cancer. In conclusion, we recommend SPON2 regulated by Notch signaling as a potential target gene to inhibit the development of gastric cancer.

SPON2 Is Upregulated through Notch Signaling Pathway and Promotes Tumor Progression in Gastric Cancer
SPON2 Is Upregulated through Notch Signaling Pathway and Promotes Tumor Progression in Gastric Cancer

PNO1, which negatively regulated by miR-340-5p, promoting the development of adenocarcinoma of the lung through the Notch signaling pathway

Many studies have shown that hyperactivation of ribosome biogenesis plays an important role in the initiation and progression of cancer. As the ribosome assembly factor, PNO1 play an important role in ribosome biogenesis. However, little is known about the expression and function in human tumors PNO1. In our study, we aimed to explore the functional role and molecular mechanisms that underlie PNO1 in human lung adenocarcinoma (LUAD). Both bioinformatics databases and tumor tissues showed that expression in tissues LUAD PNO1 higher than in the adjacent tissue and predicted poor survival in patients LUAD. In vitro and in vivo tests showed that downregulation of the expression of PNO1 suppressed cell proliferation and invasion LUAD. Further research found that miR-340-5p PNO1 depressed expression via direct binding to the 3 ‘translated region (UTR) of PNO1.

PNO1 expression negatively correlated with miR-340-5p LUAD expression in cells and tissue samples. Moreover, upregulation or downregulation of the expression of miR-340-5p reversed the inhibitory effects and excessive PNO1, respectively. Meanwhile, downregulation of Notch signaling pathway inhibits PNO1 modulated epithelial mesenchymal transition (EMT). These results indicate that PNO1, negatively regulated by miR-340-5p, plays an important role in the development of LUAD through the Notch signaling pathway. The miR-340-5p / PNO1 / Notch axis may be a potential target for the treatment of the individual and the right of patients LUAD in the future.
Forty Kunming mice were randomly divided into normal group (n = 10) and model group (n = 30).

Nephroblastoma tissue array

KD247 each
EUR 138
Description: Nephroblastoma tissue array, 24 cases/ 24 cores

Nephroblastoma tissue array

KD643 each
EUR 270
Description: Nephroblastoma tissue array, 64 cases/ 64 cores

LncRNA Profiler Complete qPCR Array Kit (cDNA synthesis kit, qPCR array and SYBR Green reagent) 20 profiles

RA910A-1 20 profiles
EUR 1329.6

Human Cell Array I

17-601 1 pack
EUR 229.2
Description: Human cell lines (HEK293, A-431, A549, Hela S3, Hep G2 and MCF7)

Human Cell Array II

17-602 1 pack
EUR 229.2
Description: Human cell lines (HL-60, Jurkat, K-562, MOLT-4, Raji and THP-1)

Tissue, Array, Human Tumor, Array II (192 Specimens/47 Pairs) (Paraffin)

MBS639724-2Slides 2Slides
EUR 680

Tissue, Array, Human Tumor, Array II (192 Specimens/47 Pairs) (Paraffin)

MBS639724-5Slides 5Slides
EUR 1255

Tissue, Array, Human Tumor, Array II (192 Specimens/47 Pairs) (Paraffin)

MBS639724-5x5Slides 5x5Slides
EUR 5490

Tissue, Array, Human Adult Normal, Array I (64 Specimens) (Paraffin)

MBS639501-2Slides 2Slides
EUR 560

Tissue, Array, Human Adult Normal, Array I (64 Specimens) (Paraffin)

MBS639501-5Slides 5Slides
EUR 915

Tissue, Array, Human Adult Normal, Array I (64 Specimens) (Paraffin)

MBS639501-5x5Slides 5x5Slides
EUR 3955

Paraffin Tissue Section Array - Human Adult Normal Tissue, Array I (64 Specimens)

T8234708-2 2 slides
EUR 325

Paraffin Tissue Section Array - Human Adult Normal Tissue, Array I (64 Specimens)

T8234708-5 5 slides
EUR 667

Multi-normal human tissue array

FDA999y3 each
EUR 355
Description: Multi-normal human tissue array,representing FDA guideline for antibody cross-reactivity testing, 99 cases/99 cores (core size 1.5mm).

Multi-normal human tissues array

FDA999w3 each
EUR 266
Description: Multi-normal human tissues array, representing FDA guideline for antibody cross-reactivity testing, 32 types of human organs, 99 cores, each type taken from 3 different individuals (core size 1.5mm).

Human Drug Detoxication I

HDTX-I 1 set
EUR 657.6

Human Drug Detoxication II

HDTX-II 1 set
EUR 774

Tissue, Array, Human FDA Standard (Frozen)

MBS639389-2Slides 2Slides
EUR 1575

Tissue, Array, Human FDA Standard (Frozen)

MBS639389-5x2Slides 5x2Slides
EUR 6870

Tissue, Array, Human Tumor (Adult), Lung (Frozen)

MBS639404-1Slide 1Slide
EUR 985

Tissue, Array, Human Tumor (Adult), Lung (Frozen)

MBS639404-5x1Slide 5x1Slide
EUR 4215

Drug Free Urine, Human Donor

MBS170675-INQUIRE INQUIRE Ask for price

Colon cancer test tissue array (4x (2x3) array)

T055a each
EUR 48
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055

Colon cancer test tissue array (4x (2x3) array)

T055b each
EUR 48
Description: Colon cancer test tissue array (4x (2x3) array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T055a

Kidney cancer test tissue array (4x (2x3)array)

T074a each
EUR 48
Description: Kidney cancer test tissue array (4x (2x3)array), including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T074

Saliva, Drug Free Human Donor

MBS173517-50mL 50mL
EUR 680

Saliva, Drug Free Human Donor

MBS173517-5mL 5mL
EUR 210

Saliva, Drug Free Human Donor

MBS173517-5x50mL 5x50mL
EUR 2855

Human Periodontal Disease Ab Array Elisa Kit

QY-E05754 96T
EUR 400

Tissue, Array, Human Tumor (Adult), Breast (Frozen)

MBS639699-1Slide 1Slide
EUR 985

Tissue, Array, Human Tumor (Adult), Breast (Frozen)

MBS639699-5x1Slide 5x1Slide
EUR 4215

Nylon Array

MVSNGA110 10 Slides
EUR 271.2

Nylon Array

MVSNGA120 20 Slides
EUR 435.6

Prostate cancer test tissue array (4x (2x3) array)

T196a each
EUR 66
Description: Prostate cancer test tissue array (4x (2x3) array), including pathology grade, Gleason grade, Gleason score, TNM and clinical stage, 6 cases/24 cores, replacing T196

Urine, Human, Ethanol & Drug Free

MBS641016-1L 1L
EUR 710

Urine, Human, Ethanol & Drug Free

MBS641016-5x1L 5x1L
EUR 3030

Tissue, Array, Human Tumor (Adult), Prostate (Frozen)

MBS639442-1Slide 1Slide
EUR 2410

Tissue, Array, Human Tumor (Adult), Prostate (Frozen)

MBS639442-5x1Slide 5x1Slide
EUR 10615

Drug Positive Urine, Human Donor

MBS170260-1Sample 1Sample
EUR 285

Drug Positive Urine, Human Donor

MBS170260-5x1Sample 5x1Sample
EUR 1100

Breast cancer tissue array and normal tissue array

BR726 each
EUR 306
Description: Breast cancer tissue array and normal tissue array, with TNM and grade, 24 cases/72 cores

Array Designer

AD6 1
EUR 5097.6

Human, Mouse, Rat - Lung Tissue Array (5 slides/pk)

TAS-1003 1 pk
EUR 343.2

FDA Standard Frozen Tissue Array - Human Adult Normal

T6234701-1 2 slides
EUR 1348

FDA Standard Frozen Tissue Array - Human Adult Normal

T6234701-2 4 slides
EUR 2500

Human, Mouse, Rat - Liver Tissue Array (5 slides/pk)

TAS-1005 1 pk
EUR 343.2

Human, Mouse, Rat - Brain Tissue Array (5 slides/pk)

TAS-1006 1 pk
EUR 343.2

Human, Mouse, Rat - Heart Tissue Array (5 slides/pk)

TAS-1009 1 pk
EUR 343.2

Human, Mouse, Rat - Colon Tissue Array (5 slides/pk)

TAS-1011 1 pk
EUR 343.2

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639569-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639569-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639569-5x5Slides 5x5Slides
EUR 4120

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639662-5Slides 5Slides
EUR 1280

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639662-5x5Slides 5x5Slides
EUR 5620

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639483-5Slides 5Slides
EUR 1280

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639483-5x5Slides 5x5Slides
EUR 5620

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639400-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639400-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Lung Tumor (Paraffin)

MBS639400-5x5Slides 5x5Slides
EUR 4120

Human, Mouse, Rat - Breast Tissue Array (5 slides/pk)

TAS-1001 1 pk
EUR 343.2

Human, Mouse, Rat - Kidney Tissue Array (5 slides/pk)

TAS-1008 1 pk
EUR 343.2

Human, Mouse, Rat - Spleen Tissue Array (5 slides/pk)

TAS-1015 1 pk
EUR 343.2

Human, Mouse, Rat - Testis Tissue Array (5 slides/pk)

TAS-1018 1 pk
EUR 343.2

Tissue, Array, Human Disease (Adult), Colon Tumor (Paraffin)

MBS639597-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Colon Tumor (Paraffin)

MBS639597-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Colon Tumor (Paraffin)

MBS639597-5x5Slides 5x5Slides
EUR 4120

Tissue, Array, Human Disease (Adult), Colon Tumor (Paraffin)

MBS639598-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Colon Tumor (Paraffin)

MBS639598-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Colon Tumor (Paraffin)

MBS639598-5x5Slides 5x5Slides
EUR 4120

Tissue, Array, Human Disease (Adult), Ovary Tumor (Paraffin)

MBS639681-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Ovary Tumor (Paraffin)

MBS639681-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Ovary Tumor (Paraffin)

MBS639681-5x5Slides 5x5Slides
EUR 4120

Human, Mouse, Rat - Stomach Tissue Array (5 slides/pk)

TAS-1013 1 pk
EUR 343.2

Lung small cell cancer array and normal lung tissue array

LC10010d each
EUR 306
Description: Lung small cell cancer array and normal lung tissue array, including TNM and clinical stage, 50 cases/100 cores (1.0), replacing LC10010c

Drug Free Urine, Pooled Human Donors

MBS170272-10L 10L
EUR 3525

Drug Free Urine, Pooled Human Donors

MBS170272-1L 1L
EUR 555

Drug Free Urine, Pooled Human Donors

MBS170272-5x10L 5x10L
EUR 15575

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639534-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639534-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639534-5x5Slides 5x5Slides
EUR 4120

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639593-5Slides 5Slides
EUR 855

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639593-5x5Slides 5x5Slides
EUR 3685

Tissue, Array, Human Disease (Adult), Rectum Tumor (Paraffin)

MBS639467-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Rectum Tumor (Paraffin)

MBS639467-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Rectum Tumor (Paraffin)

MBS639467-5x5Slides 5x5Slides
EUR 4120

Tissue, Array, Human Disease (Adult), Kidney Tumor (Paraffin)

MBS639684-5Slides 5Slides
EUR 1280

Tissue, Array, Human Disease (Adult), Kidney Tumor (Paraffin)

MBS639684-5x5Slides 5x5Slides
EUR 5620

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639728-2Slides 2Slides
EUR 595

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639728-5Slides 5Slides
EUR 950

Tissue, Array, Human Disease (Adult), Breast Tumor (Paraffin)

MBS639728-5x5Slides 5x5Slides
EUR 4120

Human Drug Transporter I Primer Library

HDTP-I 1 set
EUR 657.6

Human, Mouse, Rat - Pancreas Tissue Array (5 slides/pk)

TAS-1016 1 pk
EUR 343.2

Mouse Cell Array

17-701 1 pack
EUR 229.2
Description: Mouse cell lines (A-20, EL4, L1210, NIH/3T3, P815 and RAW 264.7)

Tissue, Array, Human Disease (Adult), Thyroid Tumor (Paraffin)

MBS639626-5Slides 5Slides
EUR 1110

Tissue, Array, Human Disease (Adult), Thyroid Tumor (Paraffin)

MBS639626-5x5Slides 5x5Slides
EUR 4855

Skin tissue array

SKN1001 each
EUR 354
Description: Skin tissue array, 50 cases/100 cores (core size 1.5mm),Recent Year Collection

Breast tissue array

BRN04a each
EUR 114
Description: Breast tissue array, 4 cases/4 cores (2.0mm), replacing BRN04

Kidney tissue array

KD803b each
EUR 354
Description: Kidney tissue array, 80 cases/80n cores (core size 1.5mm), replacing KD803a

Chordoma tissue array

BCS25011 each
EUR 270
Description: Chordoma tissue array, with P53 result, 12 cases/ 24 cores

Lymphoma tissue array

LM482c each
EUR 270
Description: Lymphoma tissue array, containing 10 cases of myeloma and normal lymph node tissue, 48 cases/48 cores, replacing LM482b

Lymphoma tissue array

NHL803e each
EUR 348
Description: Lymphoma tissue array, 80 cases/80 cores (core size 1.5mm), replacing NHL803d

Lymphoma tissue array

LY201 each
EUR 168
Description: Lymphoma tissue array, 20 cases/ 20 cores

Lymphoma tissue array

LY2087a each
EUR 546
Description: Lymphoma tissue array, 208 cases/208 cores, replacing LY2087

Lymphoma tissue array

LY302 each
EUR 168
Description: Lymphoma tissue array, 30 cases/ 30 cores (core size 2.0mm), replacing BS20011c. The previous Item# is BS20011d

Melanoma tissue array

ME483 each
EUR 270
Description: Melanoma tissue array, including TNM and clinical stage, 48 cases/48 cores, replaced by ME483a

Lymphoma tissue array

T201b each
EUR 48
Description: Lymphoma tissue array, with normal lymph node tissue, 6 cases/24 cores, replacing T201a

Lymphoma tissue array

T201c each
EUR 48
Description: Lymphoma tissue array, with normal lymph node tissue, 6 cases/24 cores, replacing T201a

Tissue, Array, Human Adult Normal, Multi-Tissue I (Frozen)

MBS639644-1Slide 1Slide
EUR 600

Tissue, Array, Human Adult Normal, Multi-Tissue I (Frozen)

MBS639644-5Slides 5Slides
EUR 1335

Tissue, Array, Human Adult Normal, Multi-Tissue I (Frozen)

MBS639644-5x5Slides 5x5Slides
EUR 5795

Ependymoma tissue array

GL151 each
EUR 238
Description: Ependymoma tissue array, including pathology grade, 15 cases/15 cores

Oncocytoma tissue array

ON481 each
EUR 138
Description: Oncocytoma tissue array, 24 cases/48 cores

Multiplex ELISA Kit For Human Micronutrient Array (7-plex)

MEK1024 1 kit
EUR 1640.4

Osteosarcoma tissue array

OS804d each
EUR 354
Description: Osteosarcoma tissue array, including TNM and clinical stage, 40 cases/80 cores, replacing OS804c

Pancreatitis tissue array

PA691 each
EUR 306
Description: Pancreatitis tissue array, including Non-neoplastic pancreatitis,normal adjacent pancreatitis and cancer adjacent pancreatitis,68 cases/69 cores, replacing BBS14011.

Leiomyosarcoma tissue array

SO804b each
EUR 270
Description: Leiomyosarcoma tissue array, including TNM and clinical stage (AJCC 7th edition), 80 cases/80 cores (core size 1.5mm), replacing SO804

Human, Mouse, Rat - Small Intestine Tissue Array (5 slides/pk)

TAS-1020 1 pk
EUR 343.2

Non-small cell lung cancer NSCLC test tissue array (4x (2x3)array)

T047a each
EUR 48
Description: Non-small cell lung cancer NSCLC test tissue array (4x (2x3)array), including TNM, clinical stage and pathology grade, 6 cases/24 cores, replacing T047

96-well Array Plate

AP-001C 1 plate
EUR 232
Description: Chromatography Reagents

Tissue, Array, Human Tumor and Normal, Multi-Tissue I (Frozen)

MBS639558-1Slide 1Slide
EUR 755

Tissue, Array, Human Tumor and Normal, Multi-Tissue I (Frozen)

MBS639558-5Slides 5Slides
EUR 1745

Tissue, Array, Human Tumor and Normal, Multi-Tissue I (Frozen)

MBS639558-5x5Slides 5x5Slides
EUR 7620

ABplex Human drug addiction Assay Kit (custermized)

RK04570 96T
EUR 3294.53

Blue Particle Array Kit

PAK-7067-9K 9X1 mL
EUR 1126.8
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Lymph node tissue array

LY481a each
EUR 168
Description: Lymph node tissue array, 24 cases/48 cores, replacing LY481

Bone marrow tissue array

BM241b each
EUR 66
Description: Bone marrow tissue array, 12 cases/24 cores, replacing BM241a

Brain tumor tissue array

T176a each
EUR 48
Description: Brain tumor tissue array, including pathology grade, 6 cases/24 cores, replacing T176

CA125 antibody array kit

VArk-Lsx008 1 mg
EUR 796.8
Description: CA125 can be used as a tumor marker to identify the type of tumor and check if the treatment is working.

Lung cancer tissue array

VLC11 each
EUR 66
Description: Lung cancer tissue array, with TNM and grade info, 11 cases/11 cores

Lung cancer tissue array

VLC12b each
EUR 66
Description: Lung cancer tissue array, including pathology grade, TNM and clinical stage, 12 cases/12 cores, replacing VLC12a

Brain tumor tissue array

GL2083c each
EUR 546
Description: Brain tumor tissue array, including pathology grade, 192 cases/192 cores (core size 1.0mm), replacing GL2083b

Brain tumor tissue array

GL242a each
EUR 270
Description: Brain tumor tissue array, with normal tissue, 2 serial sections, 24 cases/48 cores replacing GL242

Brain tumor tissue array

GL243 each
EUR 198
Description: Brain tumor tissue array, including pathology grade, 24 cases/24 cores

Brain tumor tissue array

GL803d each
EUR 306
Description: Brain tumor tissue array,including astrocytoma, glioblastoma,oligoastrocytomas,oligodendroglioma,medulloblastoma and ependymoma,80 cases/80 cores (core size 1.5mm), replacing GL803c

Lung cancer tissue array

LC1261 each
EUR 354
Description: Lung cancer tissue array, including pathology grade, TNM, clinical stage and PD-L1 (Sp263) information, 63 cases/126 cores

Lung cancer tissue array

LC243 each
EUR 198
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 2 serial sections, 24 cases/48 cores

Lung cancer tissue array

LC485 each
EUR 198
Description: Lung cancer tissue array, with normal tissue, including TNM and pathology grade, 48 cases/48 cores

Lung cancer tissue array

LC721 each
EUR 270
Description: Lung cancer tissue array, including TNM and pathology grade, 24 cases/72 cores

Normal lung tissue array

LC725 each
EUR 270
Description: Normal lung tissue array, 24 cases/72 cores, replacing BN04011

Lung cancer tissue array

LC726b each
EUR 222
Description: Lung cancer tissue array, including TNM, clinical stage and pathology grade, 72 cases/72 cores, replacing LC726

Normal lung tissue array

LCN241 each
EUR 114
Description: Normal lung tissue array, 24 cases/24 cores

Lung cancer tissue array

LUN703 each
EUR 198
Description: Lung cancer tissue array,including pathology grade and TNM,7 cases/70 cores (core size 1.5mm)

Lung cancer tissue array

NSC151 each
EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array

NSC153 each
EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array

NSC154 each
EUR 420
Description: Lung cancer tissue array, with ALK results,, 150 cases/150 cores

Lung cancer tissue array

NSC155 each
EUR 420
Description: Lung cancer tissue array, with ALK results, 150 cases/150 cores

Lung cancer tissue array

NSC156 each
EUR 420
Description: Lung cancer tissue array, 150 cases/150 cores

Lung cancer tissue array

NSC157 each
EUR 420
Description: Lung cancer tissue array, 150 cases/150 cores

Heart tumor tissue array

T301a each
EUR 48
Description: Heart tumor tissue array, with normal heart tissue, including TNM, 6 cases/24 cores, replacing T301

Frozen Tissue Array - Human Adult Normal Tissue, Multi-tissue I

T6234700-1 1 slide
EUR 292

Frozen Tissue Array - Human Adult Normal Tissue, Multi-tissue I

T6234700-5 5 slides
EUR 1104

Certified Drug Free Urine, Pooled Human Donors

MBS173716-INQUIRE INQUIRE Ask for price

Testis tumor tissue array

BC23012 each
EUR 270
Description: Testis tumor tissue array, 23 cases/63 cores

Normal brain tissue array

BNC17011a each
EUR 306
Description: Normal brain tissue array, 25 cases/ 80 cores, replaced by BNC17011b

Colon cancer tissue array

CO1502 each
EUR 258
Description: Colon cancer tissue array, including TNM, clinical stage and pathology grade, 75 cases/150 cores

Colon cancer tissue array

CRM1503 each
EUR 420
Description: Colon cancer tissue array, 150 cases/150 cores

Model of ulcerative colitis induced by free drinking of 2% dextran sulfate sodium (DSS). After 15 days, rats were divided into model group, 6-gingerenol group and positive control group with 10 rats in each group. normal group and model group were treated with normal saline, 6-gingerenol group treated with 6-shogaol 100 mg / (kg · d), the positive control group treated with sulfasalazine 100 mg / (kg · d) for 20 days. Intestinal histopathological changes were observed, and the expression of Hes-1 and Mathematics-1protein in colonic epithelial cells was detected by double immunofluorescence labeling method.

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